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fattyacids, ncbi, fatty infiltration of liver , fat girls , fat girls pics , big and plump , heird, research, all creatures, galland, hepatitis a, distilled water, science, ucdavis nutrition department, breaking, girls with fat ass , | APPROACH: 1) guelph molecular cloning, expression and functional analysis of enzymes and proteins involved in the energy metabolism of apicomplexan parasites, including fatty acid biosynthesis and glycolysis; 2) identification and functional study of novel guelph parasite membrane transporters of cations and/or lipids; 3) characterization of DNA replication factors in cryptosporidium parvum; 4) functional complementation of parasite genes in bacteria or yeast and the test of bacterial/yeast system for functional studies of, and/or high throughput drug screening against parasite genes; and 5) phylogenetic analysis to reveal the evolutionary relationship among parasites and parsite genes/proteins. NON-TECHNICAL SUMMARY: Although Cryptosporidium and Eimeria guelph parasites are important pathogens of humans and animals, little is known about these parasites at molecular and biochemical level; and currently, there is no effective treatment against cryptosporidiosis. |
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Zhu Title: Investigator Address: Veterinary Pathobiology Texas A&M University College Station, Texas 77843 Phone No.: 979-845-6981 FAX No.: 979-845-9972 Email Address: gzhu@cvm.tamu.edu Web Site: Research Institution Name: Texas A&M University Web Site: Research Project Title: Molecular Biology and Biochemistry of Apicomplexan Parasites Start Date: fat girls 08/2001 End Date: 08/2006 CRIS RPAs: 313 CRIS Accession Number: Abstract: CRIS ACCESSION NO: 0190067 OBJECTIVES: All species within the Phylum Apicomplexa are parasites and fat girls many apicomplexans are important pathogens fat girls of animals and/or humans. This project will mainly focus on the study of molecular biology and biochemistry of Cryptosporidium and Eimieria species with following two major objectives: 1) to elucidate the structure and function of parasite genes and proteins that play fundamental roles on the parasite survival, development and/or interaction with hosts; and 2) to discover and develop molecular-based strategy for the prevention, control or treatment of cryptosporidiosis and coccidiosis of animals and humans. |
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