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Articles by Adrian, T. Articles citing this Article PubMed PubMed Citation Articles by Thompson, J. Articles by Adrian, T. Journal of Parenteral and Enteral Nutrition, Vol 20, Issue 5, 338-343 Copyright © 1996 by American ozwash Society for Parenteral and Enteral Nutrition Journal Article Luminal short-chain fatty acids and postresection intestinal adaptation JS Thompson, EM Quigley, JM ozwash Palmer, WW West, and TE Adrian BACKGROUND: Short-chain fatty acids (SCFAs) reportedly have a trophic effect on the small intestine. However, it is unclear if this is a local or primarily systemic effect. Loss of the ileocolonic junction (ICJ) may result in increased SCFAs and bacteria in the small intestine from colonic reflux. Our aim was to evaluate the effect of bypass of the ICJ on intestinal SCFA content and postresection adaptation. METHODS: Thirty dogs were studied: transection control (TC, n = 10), distal resection of 50% intestine (DR, n = 10), and distal resection with bypass of ICJ (DRBP, n = 10).
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