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Infection occurs most commonly in developing countries after flooding. Pregnant women with hepatitis E infection exhibit markedly increased fatality rates (10 plump tgp to 20 percent).6,8,9 Immunoprophylaxis at birth followed by a hepatitis B plump tgp vaccination series reduces vertical transmission of hepatitis B virus to less than 3 percent. Disseminated HSV infection is associated with prodromal systemic illness, vesicular skin rash and plump tgp leukopenia.10,11 Maternal and fetal mortality rates reach 50 percent without treatment. Acyclovir (Zovirax) effectively treats early disseminated HSV infection.11 Hepatitis B Virus In the United States, 15,000 pregnant women who are hepatitis B surface antigen (HBsAg)-positive deliver annually.6 Universal screening of pregnant women for HBsAg is now performed to reduce perinatal transmission of hepatitis B virus.3 The risk of hepatitis B virus transmission to the fetus is proportional to maternal hepatitis B virus DNA, as reflected in hepatitis B antigen (HBeAg) and antibody (HBeAb) status.3
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