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permanent, symptoms of fatty liver , acute inflammation, fatty acid definition , plump black , fatty acid, plump and perky turkey , drug, busty plump , fatty infiltration liver , | Of specific interest is cryptosporidium the regulation of the enzyme stearoyl cryptosporidium CoA desaturase, which has the ability to convert saturated into monounsaturated fatty acids. The ultimate aim is to devise strategies to produce meat with a less saturated fatty acid profile. Selected Publications: IDDON,C.R., WILKINSON,J., BENNETT.A.J., BENNETT.J, SALTER,A.M. and HIGGINS,J.A. (2001) A role for smooth endoplasmic reticulum membrane cholesterol ester cryptosporidium in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2. Biochemical Journal 358, 415-422. BARBER,M.C., WARD,R.J., RICHARDS,S.E., SALTER,A.M., BUTTERY,P.J., VERNON,R.G. and TRAVERS,M.T. (2000) Ovine adipose tissue monounsaturated fat content is correlated to depot-specific expression of the stearoyl-CoA desaturase gene. Journal of Animal Science 78, 62-68. |
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Another aspect of our symptoms of fatty liver work concerns the effects of diet on the development of atherosclerosis. Working with animal models we are studying the influence symptoms of fatty liver of dietary fatty acids on the progression symptoms of fatty liver and regression of the atherosclerotic plaque. In recent years it has become clear that dietary antioxidants may play an important role in modulating the development of atherosclerosis. We are currently investigating the potential role of plant-derived antioxidant molecules in protecting lipoprotein particles from oxidation and thus influencing theatherogenic process. Meat represents a major source of dietary saturated fatty acids and hence its consumption may be associated with increased plasma cholesterol and increased risk of cardiovascular disease. Working together with Animal Biochemistry and Nutrition colleagues we are looking at factors which influence the fatty acid composition of farm animal tissues, particularly in ruminants. |
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