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Our results also indicate that the mean value of serum Tc, LDLc and FBS were significantly decrease and HDLc was significantly increased after diet therapy which was similar to the Veno T et al study16. Improvement in liver test result is almost universal in obese adults3 after weight reduction. The degree of fatty infiltration usually decreases with weight loss in most patients.3 engineering Since the actual mechanisms are still being worked out, engineering a net retention of engineering lipids within hepatocytes, mostly in the form of triglycerides, is responsible for the development of NAFLD. The primary metabolic abnormalities leading to lipid accumulation are not well understood, but they could consist of alterations in the pathways of uptake, synthesis, degradation, or secretion in hepatic lipid metabolism resulting from insulin resistance. Insulin resistance owing to inhibition of tumor necrosis factor-a (TNF-a) leads to the accumulation of fat in hepatocytes by two main mechanisms: Lipolysis, which increases circulting fatty acids and hyper insulinemia.
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