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Supplemented fasting with weight loss that is moderate and gradual can safely improve biochemical liver tests, decrease liver size and resolve fatty change in the chronic liver dicrease associated with obesity and diabetes.18 The long-term benefit of weight loss is difficult to evaluate however, plump princess because patients with NASH would plump princess have to maintain sustained reductions in weight. Surgical Procedures (Gastroplasty or Gastric Bypass) Gastric bypass or gastroplasty performed in obese patients (75% overweight) have plump princess significantly reduced steatosis from 73% to 40% one year after surgery. Discrete inflammatory changes also largely disappeared and serum alkaline phosphatase was significantly reduced. Reduction in weight during this period ranged from 12% to 42%.27 In contrast, the weight loss induced by jejunoileal (J-I) bypass operations, in most cases, seems to be accompanied by a further increase in liver steatosis and fibrosis.28 Antibiotics After jejunoileal bypass, steatohepatitis has resolved with metronidazole therapy,29 but this treatment has not been evaluated in primary NASH.
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