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| arts, judystern, milwaukee, hammersmith hospital, plump djs , military, iv drugs, herbicides, washington, sex, prostitutes, omega 3 fatty acid fish oil , plump nude women , hospital, substancedependence, health professionals, online, pleasantly plump , | We are also investigating the various roles and importance of ketone bodies in animals. We have established that two tissue specific forms of the enzyme exist in molluscs and fish infant with differing isomeric specificity. infant While terrestrial and freshwater molluscs have a well developed ketone body metabolism, marine molluscs do not express the terminal enzyme in the pathway (b-hydroxybutyrate dehydrogenase). Our work in this area involves establishing the role of ketone bodies in molluscs and infant anoxia tolerant fish. Elasmobranch metabolism. The metabolism of elasmobranch fishes differs substantially from that of virtually all other vertebrates due to the need to synthesize substantial amounts of urea for osmotic support. One manifestation of this is a reduced reliance on lipid substrates and increased reliance on ketone bodies. We are examining aspects of the role of glutamine in elasmobranch metabolism and its interaction with lipid and ketone body metabolism. |
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| These include washington investigations of a gastropod mollusc (Coxiella) from the hypersaline lakes of washington western Australia, anadromous arctic char from the Canadian Arctic as well as brackish water stingrays from Indonesia. Comparative and evolutionary aspects of metabolism: Amino acid metabolism. I have shown there are changes in the importance of amino acids as energy sources in the evolution of the vertebrates and molluscs. Our finding that the red muscle mitochondria of all fish examined to date as well as amphibians oxidize glutamine at high rate indicated a contrast with the situation in mammalian muscle which washington is a net exporter of glutamine and has little capacity for glutamine oxidation. This finding has a broad significance in understanding the metabolism of fishes in general and the evolution of metabolism in the vertebrates. We are examining the mechanisms of glutamine transport and metabolic regulation in teleost fish and elasmobranchs. Ketone body metabolism. |
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