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Prev | Table of Contents | Next Reports Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase Robert Zimmermann,1* Juliane G. Strauss,1* Guenter Haemmerle,1 Gabriele Schoiswohl,1 Ruth Birner-Gruenberger,3 Monika Riederer,1 Achim Lass,1 Georg Neuberger,2 Frank Eisenhaber,2 Albin Hermetter,3 Rudolf fat girls fucking Zechner1 Mobilization of fatty acids from fat girls fucking triglyceride stores in adipose tissue requires lipolytic enzymes. Dysfunctional lipolysis affects energy homeostasis and may contribute to the pathogenesis of obesity and insulin resistance. fat girls fucking Until now, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. Here, we report that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. It is interesting that ATGL contains a "patatin domain" common to plant acyl-hydrolases. ATGL is highly expressed in adipose tissue of mice and humans.
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