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fat girls xxx , amino acid requirements, atkinsdiet carbohydrates cholesterol, health, queen charlotte's and chelsea hospital, london, sale, comorbidity, plump nude , fatty j's pizza , potential human health, fat asian girls , fatty liver of pregnancy , heavy metals, atroshi et, exclusive, fatty acid exporters, | Metformin therapy was found to eliminate fatty liver disease in this model. The potential mechanisms of the action of metformin were the inhibition of hepatic tumor necrosis factor (TNF)alpha and several TNF-inducible responses, which are likely to promote hepatic steatosis and necrosis.In these experiments, ob/ob mice were fatty diet divided into three treatment groups. Group 1 consisted of eight mice that were treated with metformin and permitted to consume a nutritiously replete liquid mouse diet ad libitum. Mice in group 2 (n = 8) did not receive metformin but were pair-fed the same volume fatty diet of liquid diet that the fatty diet mice in the metformin-treated group had consumed on the previous day. |
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of Gastroenterology, University of Miami, fatty acid exporters School fatty acid exporters of Medicine/Mount Sinai Medical Center, Miami, Florida, USA.The study population in this report by Lin et al. was ob/ob mice that have an inherited genetic deficiency of the appetite-suppressing hormone leptin. These mice develop hyperinsulinemia, insulin resistance, and fatty livers. Compared with their lean littermates and wild-type C57BL-6 mice, ob/ob mice have hepatomegaly. In this study, the authors compared three different groups of adult mice (aged 8-10 wk), including male ob/ob C57BL-6 mice, their lean littermates, and wild-type C57BL-6 mice of the fatty acid exporters same age and sex.The primary purpose of this study was to test the efficacy of metformin for treatment of fatty liver disease in obese, ob/ob mice that develop hyperinsulinemia or insulin resistance and fatty livers. |
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