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| plump girl , plump granny , addicts, nurse, alfalfa silage, on, healthcare, study, docosahexaenoic acid, game, investigation, antiaging, fatty acid products, parenteral vitamin e, raw milk, arts, | Van de ravenscourt park hospital Auwera, et ravenscourt park hospital al. [1] reported that mice fed a ketogenic diet (<1% carbohydrate, 80% fat) were found to have a 25% decrease in the ravenscourt park hospital protein Aβ42 compared to mice fed a standard high-carbohydrate, low-fat chow diet. Aβ42 is a particularly amyloidogenic mutant form of the amyloid precursor protein whose proteolytic product β-amyloid peptide is contained in the plaques and neurofibrillar tangles that are characteristic of AD. Any suggestion of an environmental or dietary attack on AD is welcome given the devastating effects of the disease. Beyond the potential application, however, Van de Auwera, et al.'s results have general implications for nutritional approaches in biochemistry and cell biology, and ultimately on disease processes. |
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| mirrored from Nutrition & Metabolism at 09am on January 11, 2006 Nutrition & Metabolism Volume 2 • Full text • PDF (251KB) Editorial When is a high fat diet not a high fat diet? Richard D Feinman Department of Biochemistry, State University of New York Downstate Medical Center, Brooklyn, NY 11203 USA Nutrition & Metabolism 2005, 2:27 doi:10.1186/1743-7075-2-27 antiaging The electronic version of this article is the complete one and can also be found online at: http://www.nutritionandmetabolism.com/content/2/1/27 Received 4 October 2005 Accepted 17 October 2005 Published 17 antiaging October 2005 © 2005 antiaging Feinman; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The observation that a high fat/low carbohydrate (CHO) diet has a beneficial effect on a mouse model of Alzheimer's disease (AD) published today is notable given previous results showing that high fat diets have a deleterious effect on AD. |
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