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This causes increased lipolysis and transfusions excessive liberation of fatty acids which may have several effects in peripheral tissues. Thus, the regulation of the TAG-fatty acid transfusions axis may be more important than the dietary levels of fat itself. Similarity of starvation and transfusions carbohydrate restriction One of the areas bearing on the idea that disposition of fat is controlled by insulin is the observation made by several groups that the metabolic response to starvation resembles the response to carbohydrate restriction [7-11]. An important but, in our view, under-appreciated study is that of Klein & Wolfe [11] who compared responses of subjects on an 84 hour fast to the same subjects on a similar fast in which lipids were infused at a level equal to resting energy requirements. Table 1 shows that the levels of fatty acid, rates of oxidation and levels of glucose and ketone bodies were similar in the two groups (Table 1).
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