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With respect to "effect," possible effects of DHA on endpoints other than cognition cod liver oil or behavior, such as visual function, could bias the results of numerous tests, as indicated above. Thus, on the basis of these 5 causal criteria, the experimental results reviewed here supply some evidence that is cod liver oil not inconsistent with a causal connection between DHA availability and cognitive function, but they do not show causality. Finally, we comment briefly on our view of the relevance of results cod liver oil reviewed here to the question of whether infant formula should be supplemented with DHA. The experiments most directly relevant to this question obviously are human RCTs that compare performance in children fed LCPUFA-supplemented or -unsupplemented formulas. As discussed, results from these RCTs are mixed and have not consistently shown a positive effect of supplementation on cognitive or behavioral function other than intriguing results from a relatively small number of studies.
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