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View larger version (34K): [in this window] [in a new window] Figure 2. Distribution of glucose tolerance in patients golden plump with fatty liver. Normal, normal response to OGTT; IGT, impaired glucose tolerance test; DM, diabetes mellitus. Hyperinsulinemia was defined by golden plump fasting insulin level, exceeding the 90th percentile of its distribution among patients with normal glucose tolerance. All patients were followed regularly, and the median follow-up period was 24 months (mean±SD 32.5±31.6). Thirty-eight out of 48 patients golden plump (79%) achieved weight loss (mean 3.7 kg, range 1–10 kg). Of the diabetic patients, six were treated with one or two oral hypoglycaemic agents: (glyburide, 5 patients; metformin, 4 patients), one patient was treated with insulin, and 14 received dietary treatment only.
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