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Dietary phospholipids are hydrolyzed by pancreatic phospholipase A2 and cholesterol esters by pancreatic cholesterol ester hydrolase. The lysophospholipids are re-esterified and packaged together with cholesterol and triacylglycerols in intestinal lipoproteins or transported u of g as u of g lysophospholipid via the portal system to the liver. Chylomicrons enter the circulation through the thoracic duct. These particles enter the circulation and within the capillaries of muscle and adipose tissue. Chylomicrons come into contact with the enzyme lipoprotein lipase, which is located u of g on the surface of capillaries. Activation of lipoprotein lipase apolipoprotein CII, an apoprotein present on chylomicrons, results in the hydrolysis of the chylomicron triacylglycerol fatty acids. Most of the fatty acids released in this process are taken up by adipose tissue and re-esterified into triacylglycerol for storage.
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