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| girls with fat asses , plump girls , plump ass , medicine, control, editor, plump rump , pregnancy, nonmastitic glands, plump blonde , bbw plump , aspartame, metabolism, minerals, cancer, cytosolic fatty acid, ceramide plump perfect , lactation holstein, plump tits , correlation coefficients, sentinel, sexy plump , research & development, | In humans, significant differences in plasma concentrations of DHA between unsupplemented and supplemented formula comparison groups are well documented (113, 114). It is important to note that, in all of these common experimental designs that affect DHA status, DHA is not the only variable. Even in RCTs, formulas typically are supplemented with other LCPUFAs, particularly AA, big plump in addition to DHA. Thus, to different degrees, these designs have an inherent lack of big plump specificity big plump that is important to take into account in evaluating the significance of results relative specifically to DHA. Performance tests Many different kinds of tests have been used in human and animal studies. In this review, we focus primarily on tests aimed at assessing cognition or related mental functions, but a few tests assessing other correlates of functional development of the nervous system, such as neuromotor activity (115, 116) and sleep patterns (117), are also included. |
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| Most studies in animals compare offspring whose supply of ALA, the precursor of DHA, has been severely limited for different periods of time. In most rodent ALA-restriction studies, brain concentrations of DHA are dramatically reduced in test animals, by as much as 85% (101), and decreases of 75% in nonhuman primates have aspartame been reported (64). It is important, however, that some studies in rodents also used dietary conditions that resulted in smaller decreases in brain DHA (40, 102–105). Human autopsy aspartame studies reported significant aspartame differences of 11% to 40% in DHA concentrations in brain gray matter between breastfed and unsupplemented formula-fed infants (106–110); two further references provide review (4, 111). Direct autopsy evidence that compares brain DHA concentrations in human infants fed unsupplemented and LCPUFA-supplemented formulas is not available. However, a recent autopsy study in nonhuman primates reported 30% lower concentrations of DHA in the visual cortex of preterm infants fed unsupplemented formula than in those fed LCPUFA-supplemented formula (112). |
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