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Scatterplot showing observed versus predicted ratios of serum total to HDL cholesterol. Each point refers to a specific test intron diet in one of the studies. "Predicted" values were calculated as the intron intrinsic concentration of the group under study plus the predicted change induced by their test diet (see Table 1). The intrinsic concentration reflects the total:HDL cholesterol intron that would result if this particular group of subjects consumed a standardized fat-free, high-carbohydrate diet. It is determined by factors such as genetic makeup, age, and body mass index and by factors such as the fiber, protein, or alcohol content of the background diet, which was constant within studies but differed between studies. (Carbohydrates SFAs), (Carbohydrates MUFAs), and (Carbohydrates PUFAs), percentage of energy in the form of carbohydrates replaced with an equal percentage in the form of saturated fatty acids, cis monounsaturated fatty acids, or cis polyunsaturated acids, respectively.
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