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Canavan obesity Disease Canavan disease is a rare inherited neurological disorder characterized by spongy degeneration of the brain and spinal cord. Symptoms that appear in early infancy may include progressive mental decline accompanied by the loss of muscle obesity tone, poor head control, an abnormally large head, and/or irritability. Source: WebMD Advertisement Ashtyn is one of only 21 participants from the United States, Europe and South America in an enterprising clinical trial where researchers pump genes into the brain in hopes of improving motor skills and brain function. A floppy head and stiff limbs are trademarks of the disorder. Other symptoms obesity include mental retardation, blindness, deafness and paralysis. Chemical builds up In Canavan disease, a malfunctioning gene causes a buildup in the brain of a chemical called N-acetyl aspartate.
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