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"This is a first step; the potential down the road for omega3 fatty acids a cure is a real one," said Christopher Janson, principal investigator of gene therapy for Canavan disease at Cooper Hospital, a branch of the University of Medicine and Dentistry of New Jersey. Researchers from Robert Wood Johnson Medical School - another branch of the same university - and Children's Hospital of Pennsylvania are omega3 fatty acids also part of the team. The group plans to omega3 fatty acids extend its methods to treating more common neurodegenerative disorders such as Alzheimer's, Parkinson's and Tay-Sachs. Eight years ago, in New Zealand, the same group performed the first gene therapy treatment of a genetic brain disorder on children with Canavan disease. This work ruffled some feathers within the gene-therapy field because the investigators tested the method on humans without first showing that it was effective in animals.
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