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Figure 1 PUFA synthesis from parent essential fatty acids LA: linoleic acid; GLA: gamma-linolinolenic acid; DGLA: dihomogammalinolenic acid; AA: arachidonic acid; ALA: alpha-linolenic acid; EPA: eicosapentanoic acid. In the shorthand notation used here, the first number denotes the number clinical mastitis of carbon atoms in the fatty acid molecule, and the number after the colon denotes the number of double bonds it contains. Membrane Phospholipid Turnover The cell membrane is in a constant state of flux: fatty acids clinical mastitis are released from the membrane by phospholipases (Figure 3). PLA2 can release AA, DGLA, and clinical mastitis EPA from the sn-2 position of membrane phospholipids, but with vastly differing consequences: DGLA and AA (both omega-6), as well as EPA (omega-3), can be transformed into prostaglandins and thromboxanes of the 1-, 2-, and 3-class, respectively.
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